20200812 News Clippings – The Russian Vaccine, Dr. Gupta not sending kids back to school, Kamala Harris

Wednesday, 12 August, 2020

20200812 News Clippings

20200811, Science Mag, “The Russian Vaccine”

“Many will have heard Russia’s announcement that they have approved a coronavirus vaccine. I’ve already had several people ask me what I think of it, so let me be clear: I think it’s a ridiculous publicity stunt. If it’s supposed to make Russia look like some sort of biotechnology powerhouse, then as far as I’m concerned it does the opposite. It makes them look desperate, like the nation-state equivalent of a bunch of penny-stock promoters. The new airliner design prototype just got off the ground – time to sell tickets and load it full of passengers, right?

Why so negative? Look at what’s being claimed – the first coronavirus vaccine to receive regulatory approval. But “regulatory approval” is not some international gold standard, and these sorts of decisions show you why. Let’s be honest: there is no way that you can responsibly “approve” a vaccine after it’s only been into human trials for what numerous reports say is less than two months. That’s about enough time to do the first steps, a Phase I trial that gives you some idea of immune response across more than one dose. It is simply not enough time to do a reasonable efficacy workup as well, and absolutely not enough time to get any sort of reading on safety. Here’s a good article going into those timelines in more depth.”

20200812, CNN, “Dr. Sanjay Gupta: Why I am not sending my kids back to school”

20200812, NYT, “Why Kamala Harris Matters to Me”

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20200624 Kick at the darkness ’til it bleeds daylight

Thursday, 25 June, 2020

Posts from 20200624

1a) #GreatPodcast #LoversInADangerousTime “Got to kick at the darkness ’til it bleeds daylight”
On this Tuen Ng Festival (#端午節), here is a heartbreaking, heartwarming, and insightful podcast to listen.

#FrontBurner //One woman’s fight to free her husband from a Chinese jail//

//In an exclusive interview this week with The National’s Adrienne Arsenault, Michael Kovrig’s wife spoke out for the first time.

Vina Nadjibulla says Ottawa could do more to get her husband — and Canadian Michael Spavor — out of jail in China. Both men were arrested in December of 2018 just days after Huawei executive Meng Wanzhou was detained in Vancouver on behalf of American justice officials.

Today on Front Burner, Arsenault brings us more on Nadjibulla’s fight for her husband’s freedom — and how she is helping him stay resilient.//

1b) 20200622 //Michael Kovrig’s wife on fighting for his freedom: exclusive interview//

//Michael Kovrig’s wife (though separated) Vina Nadjibulla speaks for the first time in an exclusive interview with Adrienne Arsenault about his detention, Canada’s diplomacy and her fears for the future. Nadjibulla also shares letters Kovrig has sent during his 560 days in a Chinese prison.

#MichaelKovrig
#MichaelSpavor
#China
#Huawei//

2) Two great answers from Dr. Mike & Dr. Maria (WHO 20200624 WHO Media briefing on COVID-19)

WHO official transcript PDF link: https://www.who.int/docs/default-source/coronaviruse/transcripts/virtual-press-conference—24-june—covid-19.pdf

38:08 MR (from WHO official transacript) “If I could add on this, we tend to get positive information on remdesivir and we all chase that for a while and then we get stuff on dexamethasone and then we have a discussion about oxygen and then we have a discussion about other things.I think we need to really start seeing this as how do we optimise the clinical management of all patients who become sick; from the very moment that someone feels sick, getting an early diagnosis, being able to see a qualified physician or nurse and understanding, that physician or nurse being able to understand your underlying conditions, your likely risk and being able to put you into a pathway to see and seek and have the right care available. […]”

42:52 MK “That’s really a fantastic question. We are living in a time right now where there’re so many different groups that are carrying out really incredible research, real-time research right now for a new virus that we didn’t know anything about six months ago.We are learning about severity, we’re learning about transmission, we’re learning about treatments, we’re learning about every aspect of this virus and it’s happening at an incredibly rapid pace so that’s very positive. We’re seeing innovation in areas that we hadn’t seen before. You’ve mentioned the use of masks and we talk about different types of fabrics. That didn’t exist a few months ago.”

3) 20200624 Presser – Trudeau addresses calls to intervene in Meng Wanzhou case, announces investments for students | FULL

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Ditch #complicated #remdesivir #Patent2017 and focus on #GS441524 #Simpler #Safer #ancestor #Patent2009?

Thursday, 14 May, 2020

The following news is highly technical #Chemical #Pharmaceutical #Covid19 science. If I may share with you my trick and general approach to learning: I often try to read something and understand it as much as I can KNOWING I don’t know a LOT. Knowing what questions to ask and what we don’t know is part way to understanding/”some minor progress in understanding” new cutting edge science. To quote a Quote I LOVE by the Nobel Economist Ronald Coase when he was 100 years old, “You don’t know what you can learn until you try to learn.”

Have a read of May 14, 2020, Stat News, “Gilead should ditch remdesivir and focus on its simpler and safer ancestor” By Victoria C. Yan and Florian L. Muller  [HT Gabriel @gmleunghku for his RT this morning, I saw the STAT News op-ed but his RT put it more on my radar]

Here is an excerpt from //Opinion: Gilead has another antiviral that’s easier to make and safer to use than remdesivir. Why isn’t it giving that drug any attention? The world can only hope it isn’t for the sake of protecting its intellectual property.//

“The attractive profile of GS-441524 from both manufacturing and clinical perspectives raises this question: Why hasn’t Gilead opted to advance this compound to the clinic? We would be remiss for not mentioning patents, and thus profits. The first patent on GS-441524 was issued in 2009, while the first patent for remdesivir was issued in 2017.

We aren’t the only ones questioning Gilead’s strategy. We have spoken with a number of chemists, biochemists, veterinarians, and others who are also surprised that GS-441524 has remained out of the spotlight. Veterinarians we spoke to have noted that the strong antiviral activity of GS-441524 has resulted in a “miraculous turn of events” for cats infected with feline coronavirus, which was once considered a death sentence.

Given GS-441524’s optimal properties, we — along with the millions of people awaiting an effective treatment for Covid-19 — are left to wonder why Gilead isn’t giving it the same attention it is giving remdesivir. The world can only hope it isn’t for the sake of protecting its intellectual property.”

[NOTE: Do NOT take experts’ words blindly but let them highlight potentially interesting questions or where cutting edge science is]

P,S, In the 90s, I, for no good reasons that I can remember and may be I had too much money to waste/spend, subscribed to The New England Journal of Medicine for one full year! May be it was to broaden my understanding of medical science, better armed myself to read medical research, or simply to reduce my fear of reading research papers that I really know very little! I particular enjoy, if I remember right, reading the concluding paragraphs of many research papers talking about what’s “NEXT” for the researchers, what were their “unknowns”!

Gilead should ditch remdesivir and focus on its simpler and safer ancestor - pix

Gilead should ditch remdesivir and focus on its simpler and safer ancestor – pix


Jewel talks Art of Mindfulness and sings “Hands,” Discusses Song’s Origin

Wednesday, 29 April, 2020

2020 April 28, great  101.1 CBS-FM radio interview by Brad Blanks, “Brad Blanks Discusses the Art of Mindfulness and Meditation with Jewel “All meditation is being constantly present”

And I googled around and found this GREAT clip “Jewel Sings “Hands,” Discusses Song’s Origin” to watch!

Here is “Jewel – Hands (Official Music Video)”


Principal Legal Officer @WHO Steven Solomon talks #Taiwan

Wednesday, 15 April, 2020

In this press conference, Steven Solomon, WHO Principal Legal Officer talks Taiwan starting at the 17:54 mark.

===

1:46 Dr Tedros WHO Director-General opening statement and a bit of history of WHO and UN
13:50 Q1 NBC: Exact amount of US funding (minus private contribution from Gates Foundation, etc)
14:25 A1 WHO DG:
15:05 Q2 The Lancet (?):
15:50 A2
16:15 Q3 NHK re Taiwan
16:54 A4a Dr. Mike Ryan: Multiple sources of info on Dec 31, 2019. Including directly from Wuhan Health Authority …
17:54 A4b1 Steven Solomon, WHO Principal Legal Officer talks Taiwan
22:52 A4b2 Steven Solomon: 5 more examples
24:59 A4c Dr Maria Van Kerkhove speaks about her experience briefing Taiwan experts.
26:26 Q5 Russia news agency
26:54 A5 Dr. Mike Ryan

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What If the Slowest Horse Win in a Burning Racecourse Challenge? #Covid19

Monday, 13 April, 2020
Slowest Horse Wiin Tweet Challenge + Co-opetition book

Slowest Horse Wiin Tweet Challenge + Co-opetition book

(#GameTheory Part 1 of 2) The #Challenge: 🔥Fire🔥 struck @KemptonParkRace Course during imaginary (NOT real) 10-horse race! Instead of Fastest horse winning, the SLOWEST horse will WIN this race! 9 horses have human jockeys. 1 horse is ridden by #covid19. Suggest an idea to save ALL humans+determine a winner at the same time?
#TeamHuman vs #TeamCovid19 Challenge #FuckCovid19 (version 2.0)

#MySolution: So my solution is first recognizing the name of the game is suggest ***any idea***. Any idea including changing the “game itself”. So I suggest this (there may be other ways):

Instead of everyone standing there, including covid19, waiting to find a winner (the slowest horse) while being burned. Tell everyone to switch horses. So one of the human jockeys have the covid19’s horse. In fact, send the best of the human riders to ride covid19’s horse to try to “win” the race , guaranteeing it will NOT be the slowest.

And the other 8 human riders’ jobs are, well, think of it, can do anything! Doesn’t matter. I originally think of the 8 riders working together trying to block covid19 from riding to cross the finish line. But then as long as covid19’s horse get pass the finish line the 2nd, then well, it won’t win!
The core #OutOfTheBox idea is to change the game that they are playing. From riders riding their own horse to try to be the slowest. To riders riding others’ horse and to “win” to race fastest.

I saw this idea some years ago but adapted it to this challenge.

If we Think #TeamHuman vs #TeamCovid19 Challenge …
the idea is once we realize #TeamHuman should really work together. who “win” in terms of inventing or discovering a vaccine (making lots of money), who “win” in terms of making a lot of ventilators needed by the world (again making boat load of money), etc DOES NOT matter that much because all humanity wins! We just want to get #TeamCovid19 to lose.

====

Think about it some more. Once the idea of suggesting the 9 jockeys and covid19 switch horses. The game is OVER for covid19. It will take super stupid humans to let Covid19 win. Because they have to let covid19’s horse to be the slowest which I hope #TeamHumanity is NOT that dumb to have let happened!

====

Yeah, it is game over when covid19 horse is first to finish in this new game! And in fact, it is game over for covid19’s horse to finish from 1st to 9th. Just, please, the human riders don’t let covid19’s horse to go 10th because that means covid19 win.

So by changing the rule of the game, or putting the game in a different mindset, all humans win. Instead of everyone sitting at the racecourse waiting, waiting, waiting to be the slowest …
Kinda like an anology for we different countries (China, Taiwan, USA, Iran, …) fighting each other while covid19 infecting and killing us 24/7 non-stop around the clock and around the world! Super horrible!

====

In Game Theory, there is an idea call Non-Zero Sum game. And if we don’t like the game we are play, we can and should just try to change the game! Remember, in real life, we can strive to create Win-Win games and play those instead!

====

(#GameTheory Part 2 of 2) Years ago in my MBA school days, I took a class in Negotiation. In the first class, we MBA students were put into groups of two and told to conduct an negotiation exercise. At the end of these group exercises, the professor asked what negotiated outcome we came to at the end.

My classmate J (I don’t want to embarrass J but I think there is nothing to be embarrass of) and I came to a result that has such a massive big differences in the whole class! Basically, I “gained” the most advantage over J on the surface! The professor and the whole class likely came to the simplistic conclusion that I managed to majorly and royally screwed J.

My professor and my classmates were WRONG if they thought I had screwed J. I only play WIN-WIN games even then!

I, at the time, had done some “for fun” studies of negotiation by reading some business books and articles about negotiation. I was NOT merely playing the basic game of the single negotiation task that the professor assigned the whole class.

I explicitly and deliberately CHANGED the game that my classmate J and I were playing by expanding it. I suggested, which J and I agree to expand the figurative “pie” we were playing by making it 30x or 100x times bigger than before.

So effectively J and I were making a ton more $$ (or whatever) when the game itself was expanded massively.

I wish my MBA professor was more knowledgable and recognized that I was playing a different game. But then the professor had a course outline and stuff to cover so she missed a good #TeachableMoment.

Anyway, by me Turning the professor’s Zero-Sum game into a NON-ZERO-Sum game, it makes a world of a difference!

As a funny aside. I was such a rebel that the class paper she assigned us to write, I instead wrote about something else. She scored me badly like a “B-“ or something which is OK. I got to write about the more important things I learn about Negotiation which I LOVE and the ideas were from the great book:

“Co-opetition: A Revolution Mindset that Combines Competition and Cooperation” by business strategy, and game theory professors Adam M. Brandenburger and Barry J. Nalebuff.

I went to MBA school to try to learn, not just to get “good” grades. Good “grades” by themselves are pointless. Anyway, sorry my dear MBA professor for dissing you in this FB post so many years later. I bet you don’t remember me. And I didn’t name name.

Hope you are well and healthy in our covid19 time!


True Face of #Humanity, Deepfake of #Tedros #Covid19 #Avengers #InfinityWar #EndGame #TheEnd

Monday, 13 April, 2020

In “Humanity: Infinity War” against #covid19, Humanity got exactly one out of 14,000,605 futures to defeat #covid19! And we stupid humanity is now looping, wasting valuable #time fighting amongst ourselves so badly, that the movie production of “Humanity: Endgame” is basically being cancelled because we all (you, me, the smart people who made the deepfake video of Dr. Tedros & Xi Jinping, everyone of us) do not really deserve to have a slightly happier ending remotely like what “Humanity: Endgame” could have been.

At this rate, all we deserve is “Humanity: The End” as a sequel. And you know what will that movie show? You see, “Humanity: The End” is not even a brand new movie but just a duplicate copy of “Humanity: Infinity War“, so no one need to waste time doing another deepfake video. We just need to show half of humanity dead like Avengers: Infinity War. We all happy?

I wrote my first-person narrative documentary poetry “I am the F**King Virus” (now a short film), this is how I ended my poem, no one can accuse me of sugarcoating it:

//Unless Humanity stops her infighting and work together as One to end me now
I will be back//

It turns out my documentary poetry has been written based on solid provable science (so far) and too painfully real observations of humanity and how stupid we are!

#FuckingStupid

deep fake of Dr. Tedros, WHO (merging with Xi Jinping)

deep fake of Dr. Tedros, WHO (merging with Xi Jinping)

====

Note: I wrote this post originally as a comment for a wise friend but I like it enough to share it publicly.

“I am the F**King Virus” – a #Covid19 Pandemic Documentary Poetry short film

(the “14,000,605” reference) Doctor Strange Looks into the Future| Avengers Infinity War )

xxx


I am the F**King Virus – a Pandemic #Covid19 Documentary Poetry short film

Thursday, 9 April, 2020

“I am the F**King Virus” is Kempton‘s first foray into Poetry, specifically Documentary Poetry (see note below), and even more specifically the form of Documentary Poetry short film.

==== See Director’s statement plus more reference notes below after the documentary poetry ====

I am the F**King Virus – a Documentary Poem by Kempton

(20200417 version 2.48163264128256512102420484096)

I am the F**King Virus

You covered me up. And let me killed thousands

Thank you. Xie Xie. Or is it Xi Xi

WHO studied me and recommended how to beat me

but few read her report so I infected 100,000s more

How do I say thank you in Italian, Spanish, German, Persian, French, Korean, and Trumpian

I am the F**King Virus

We shall fight on the beaches

We shall fight under the cherry blossom trees

We shall fight in the churches, mosques, and synagogues

We shall fight in close combat less than 2 meters apart (with no Physical Distancing)

We can stop fighting now IF you accept my price of 1.4% of you ALL
(mostly elderly, the weak plus some healthy young human beings)

I am the F**King virus

I am on the Edge of Tomorrow or is it Live Die Repeat Read the rest of this entry »


WWIII #covid19 Human Spirit

Tuesday, 31 March, 2020

In humanity’s WWIII against #covid19, a disease that infects and kills exponentially, keeping our human spirit high is important for our long war. Here are some examples.

20200331, CTV News (with video), “Calgary teachers find socially distant way to celebrate principal’s retirement: a parade


WWIII #covid19 Medical Equipments and Supply Chains

Tuesday, 31 March, 2020

In humanity’s WWIII against #covid19, a disease that infects and kills exponentially, our medical equipments supplies (e.g. PPE (Personal Protective Equipments), face shields, etc) are in severe shortage in Canada, US, and globally. Even our Supply Chains are under attack and severe stress. This post is meant to collect some good news from our battle fronts.

20200331, Calgary Herald, “Corbella: Donated RVs help health-care workers isolate from families

20200331, WaPo, “3-D printing face shields for hospitals in need

Crystal Blair, Truck Stop Owner on Nova Scotia highway offering free meals

Crystal Blair, Truck Stop Owner on Nova Scotia highway offering free meals

20200328, CTV News (with video), “As COVID-19 puts strain on truckers, this truck stop is offering free meals

20200326 KTVQ News (video), “Montana truck stop giving goodie bags to truckers

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